First and foremost, regardless of the new features 2010 brings us, you need to look at the System Requirements.

You can find these at the
Autodesk website and choosing
AutoCAD MEP from the product list.
You'll see System Requirements on the left hand menu.

It is also important to note where to find and how to understand the importance of the Certified Hardware list.
It's not easy to find. It can only be found under AutoCAD. I know, it SHOULD be under every AutoCAD based product, but this is where you find it. That's probably another reason that not enough people are aware of it.

Choose Support under the left hand menu of the AutoCAD page.

Then you will choose Data & Downloads.

You will see Certified Hardware listed on this page.

This list contains all the graphics cards that Autodesk has tested and shows you, depending on the options you check, which ones perform better.
One of the biggest mistakes I see from users or especially their IT Departments is that they fail to order new computers with the correct graphics cards. Perhaps they asked someone that didn't give them good information or outdated information.
Many times people have the misconception that gaming computers or gaming graphics cards are the best and therefore should work for AutoCAD. That couldn't be any further from the truth.
The list is hard to find and of course there is a chance that you might have a graphics card that they have not tested that works fine. Still, the best chance at problem-free operation is to start off right with a graphics card that has been tested and performs well.